Human Activated Protein C

Human Activated Protein C
Catalog Number: APC
Size: 0.1 mg, 1.0 mg
Activated Protein C (APC) is a serine protease derived from the two chain vitamin K dependent zymogen, Protein C. APC inhibits blood coagulation through the selective inactivation of the cofactors Va and VIIIa. APC is prepared from protein C by activation with purified thrombin. This thrombin is removed after activation by ion exchange chromatography. Activated Protein C purity is determined by SDS-PAGE and shows complete reduction upon incubation with 2-mercaptoethanol.

Buffer composition = 20 mM Tris-HCl/0.1 M NaCl/ pH 7.4
Extinction Coefficient (1%) = 14.5
Molecular Weight = 56,000 daltons

Human Activated Protein C SampleĀ Certificate of Analysis

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Related: APCi, APC-GD